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Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture
Topological domains are key architectural building blocks of chromosomes, but their functional importance and evolutionary dynamics are not well defined. We performed comparative high-throughput chromosome conformation capture (Hi-C) in four mammals and characterized the conservation and divergence...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542312/ https://www.ncbi.nlm.nih.gov/pubmed/25732821 http://dx.doi.org/10.1016/j.celrep.2015.02.004 |