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Human cell dedifferentiation in mesenchymal condensates through controlled autophagy

Tissue and whole organ regeneration is a dramatic biological response to injury that occurs across different plant and animal phyla. It frequently requires the dedifferentiation of mature cells to a condensed mesenchymal blastema, from which replacement tissues develop. Human somatic cells cannot re...

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Detalles Bibliográficos
Autores principales: Pennock, Rebecca, Bray, Elen, Pryor, Paul, James, Sally, McKeegan, Paul, Sturmey, Roger, Genever, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542335/
https://www.ncbi.nlm.nih.gov/pubmed/26290392
http://dx.doi.org/10.1038/srep13113