The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis

Prion diseases are infectious neurodegenerative disorders characterized by accumulations of abnormally folded cellular prion protein in affected tissues. Many natural prion diseases are acquired orally, and following exposure, the early replication of some prion isolates upon follicular dendritic ce...

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Detalles Bibliográficos
Autores principales: Donaldson, David S., Else, Kathryn J., Mabbott, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542385/
https://www.ncbi.nlm.nih.gov/pubmed/26157121
http://dx.doi.org/10.1128/JVI.01544-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542385/
https://www.ncbi.nlm.nih.gov/pubmed/26157121
http://dx.doi.org/10.1128/JVI.01544-15

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