Development, validation of liquid chromatography-tandem mass spectrometry method for simultaneous determination of rosuvastatin and metformin in human plasma and its application to a pharmacokinetic study

A new, simple and accurate liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for simultaneous determination of rosuvastatin (ROS) and metformin (MET) in human plasma was developed. The assay procedure involved simple protein precipitation with acetonitrile. Following precipitation, fr...

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Detalles Bibliográficos
Autores principales: Kumar, P. Pavan, Murthy, T. E. G. K., Basaveswara Rao, M. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542398/
https://www.ncbi.nlm.nih.gov/pubmed/26317076
http://dx.doi.org/10.4103/2231-4040.157982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542398/
https://www.ncbi.nlm.nih.gov/pubmed/26317076
http://dx.doi.org/10.4103/2231-4040.157982

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