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Application of quality by design approach to optimize process and formulation parameters of rizatriptan loaded chitosan nanoparticles
The purpose of present study was to optimize rizatriptan (RZT) chitosan (CS) nanoparticles using ionic gelation method by application of quality by design (QbD) approach. Based on risk assessment, effect of three variables, that is CS %, tripolyphosphate % and stirring speed were studied on critical...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542404/ https://www.ncbi.nlm.nih.gov/pubmed/26317071 http://dx.doi.org/10.4103/2231-4040.157983 |