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Application of quality by design approach to optimize process and formulation parameters of rizatriptan loaded chitosan nanoparticles

The purpose of present study was to optimize rizatriptan (RZT) chitosan (CS) nanoparticles using ionic gelation method by application of quality by design (QbD) approach. Based on risk assessment, effect of three variables, that is CS %, tripolyphosphate % and stirring speed were studied on critical...

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Detalles Bibliográficos
Autores principales:	Shirsat, Ajinath Eknath, Chitlange, Sohan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542404/ https://www.ncbi.nlm.nih.gov/pubmed/26317071 http://dx.doi.org/10.4103/2231-4040.157983

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