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Progress toward overcoming hypoxia-induced resistance to solid tumor therapy

Hypoxic tumors are associated with poor clinical outcome for multiple types of human cancer. This may be due, in part, to hypoxic cancer cells being resistant to anticancer therapy, including radiation therapy, chemotherapy, and targeted therapy. Hypoxia inducible factor 1, a major regulator of cell...

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Detalles Bibliográficos
Autores principales: Karakashev, Sergey V, Reginato, Mauricio J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542411/
https://www.ncbi.nlm.nih.gov/pubmed/26316817
http://dx.doi.org/10.2147/CMAR.S58285