GPR43 Potentiates β-Cell Function in Obesity

The intestinal microbiome can regulate host energy homeostasis and the development of metabolic disease. Here we identify GPR43, a receptor for bacterially produced short-chain fatty acids (SCFAs), as a modulator of microbiota-host interaction. β-Cell expression of GPR43 and serum levels of acetate,...

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Detalles Bibliográficos
Autores principales: McNelis, Joanne C., Lee, Yun Sok, Mayoral, Rafael, van der Kant, Rik, Johnson, Andrew M.F., Wollam, Joshua, Olefsky, Jerrold M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542437/
https://www.ncbi.nlm.nih.gov/pubmed/26023106
http://dx.doi.org/10.2337/db14-1938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542437/
https://www.ncbi.nlm.nih.gov/pubmed/26023106
http://dx.doi.org/10.2337/db14-1938

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