GLP-1 Cleavage Product Reverses Persistent ROS Generation After Transient Hyperglycemia by Disrupting an ROS-Generating Feedback Loop

The assumption underlying current diabetes treatment is that lowering the level of time-averaged glucose concentrations, measured as HbA(1c), prevents microvascular complications. However, 89% of variation in risk of retinopathy, microalbuminuria, or albuminuria is due to elements of glycemia not ca...

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Detalles Bibliográficos
Autores principales: Giacco, Ferdinando, Du, Xueliang, Carratú, Anna, Gerfen, Gary J., D’Apolito, Maria, Giardino, Ida, Rasola, Andrea, Marin, Oriano, Divakaruni, Ajit S., Murphy, Anne N., Shah, Manasi S., Brownlee, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542449/
https://www.ncbi.nlm.nih.gov/pubmed/26294429
http://dx.doi.org/10.2337/db15-0084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542449/
https://www.ncbi.nlm.nih.gov/pubmed/26294429
http://dx.doi.org/10.2337/db15-0084

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