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DNA Methylation Variants at HIF3A Locus, B-Vitamin Intake, and Long-term Weight Change: Gene-Diet Interactions in Two U.S. Cohorts

The first epigenome-wide association study of BMI identified DNA methylation at an HIF3A locus associated with BMI. We tested the hypothesis that DNA methylation variants are associated with BMI according to intake of B vitamins. In two large cohorts, we found significant interactions between the DN...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Zheng, Yan, Qi, Qibin, Xu, Min, Ley, Sylvia H., Li, Yanping, Kang, Jae H., Wiggs, Janey, Pasquale, Louis R., Chan, Andrew T., Rimm, Eric B., Hunter, David J., Manson, JoAnn E., Willett, Walter C., Hu, Frank B., Qi, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542450/
https://www.ncbi.nlm.nih.gov/pubmed/26001398
http://dx.doi.org/10.2337/db15-0264