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Adult hippocampal neurogenesis and pattern separation in DG: a role for feedback inhibition in modulating sparseness to govern population-based coding

The dentate gyrus (DG) of mammals harbors neural stem cells that generate new dentate granule cells (DGCs) throughout life. Behavioral studies using the contextual fear discrimination paradigm have found that selectively augmenting or blocking adult hippocampal neurogenesis enhances or impairs discr...

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Detalles Bibliográficos
Autores principales: McAvoy, Kathleen, Besnard, Antoine, Sahay, Amar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542503/
https://www.ncbi.nlm.nih.gov/pubmed/26347621
http://dx.doi.org/10.3389/fnsys.2015.00120