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Self protein-protein interactions are involved in TPPP/p25 mediated microtubule bundling

TPPP/p25 is a microtubule-associated protein, detected in protein inclusions associated with various neurodegenerative diseases. Deletion analysis data show that TPPP/p25 has two microtubule binding sites, both located in intrinsically disordered domains, one at the N-terminal and the other in the C...

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Detalles Bibliográficos
Autores principales: DeBonis, Salvatore, Neumann, Emmanuelle, Skoufias, Dimitrios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542545/
https://www.ncbi.nlm.nih.gov/pubmed/26289831
http://dx.doi.org/10.1038/srep13242