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A Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4

Activation of macrophages triggers the release of pro-inflammatory cytokines leading to inflammation. Numb is a negative regulator of Notch signaling, but the role of Numb in macrophages is not fully understood. In this study, the role of Numb as a regulator of inflammatory responses in macrophages...

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Detalles Bibliográficos
Autores principales: Kueanjinda, Patipark, Roytrakul, Sittiruk, Palaga, Tanapat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542673/
https://www.ncbi.nlm.nih.gov/pubmed/26244698
http://dx.doi.org/10.1038/srep12784