Cargando…

Tumor Suppressor WWOX inhibits osteosarcoma metastasis by modulating RUNX2 function

Osteosarcoma (OS) is among the most frequently occurring primary bone tumors, primarily affecting adolescents and young adults. This malignant osteoid forming tumor is characterized by its metastatic potential, mainly to lungs. We recently demonstrated that WW domain-containing oxidoreductase (WWOX)...

Descripción completa

Detalles Bibliográficos
Autores principales: Del Mare, Sara, Aqeilan, Rami I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542681/
https://www.ncbi.nlm.nih.gov/pubmed/26256646
http://dx.doi.org/10.1038/srep12959