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Tumor Suppressor WWOX inhibits osteosarcoma metastasis by modulating RUNX2 function
Osteosarcoma (OS) is among the most frequently occurring primary bone tumors, primarily affecting adolescents and young adults. This malignant osteoid forming tumor is characterized by its metastatic potential, mainly to lungs. We recently demonstrated that WW domain-containing oxidoreductase (WWOX)...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542681/ https://www.ncbi.nlm.nih.gov/pubmed/26256646 http://dx.doi.org/10.1038/srep12959 |