Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor

Neoculin (NCL) is a heterodimeric protein isolated from the edible fruit of Curculigo latifolia. It exerts a taste-modifying activity by converting sourness to sweetness. We previously demonstrated that NCL changes its action on the human sweet receptor hT1R2-hT1R3 from antagonism to agonism as the...

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Detalles Bibliográficos
Autores principales: Koizumi, Taichi, Terada, Tohru, Nakajima, Ken-ichiro, Kojima, Masaki, Koshiba, Seizo, Matsumura, Yoshitaka, Kaneda, Kohei, Asakura, Tomiko, Shimizu-Ibuka, Akiko, Abe, Keiko, Misaka, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542694/
https://www.ncbi.nlm.nih.gov/pubmed/26263392
http://dx.doi.org/10.1038/srep12947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542694/
https://www.ncbi.nlm.nih.gov/pubmed/26263392
http://dx.doi.org/10.1038/srep12947

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