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Phenome-driven disease genetics prediction toward drug discovery

Motivation: Discerning genetic contributions to diseases not only enhances our understanding of disease mechanisms, but also leads to translational opportunities for drug discovery. Recent computational approaches incorporate disease phenotypic similarities to improve the prediction power of disease...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Li, Li, Zhang, Guo-Qiang, Xu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542779/
https://www.ncbi.nlm.nih.gov/pubmed/26072493
http://dx.doi.org/10.1093/bioinformatics/btv245