Misassembly detection using paired-end sequence reads and optical mapping data

Motivation: A crucial problem in genome assembly is the discovery and correction of misassembly errors in draft genomes. We develop a method called misSEQuel that enhances the quality of draft genomes by identifying misassembly errors and their breakpoints using paired-end sequence reads and optical...

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Detalles Bibliográficos
Autores principales: Muggli, Martin D., Puglisi, Simon J., Ronen, Roy, Boucher, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Ismb/Eccb 2015 Proceedings Papers Committee July 10 to July 14, 2015, Dublin, Ireland
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542784/
https://www.ncbi.nlm.nih.gov/pubmed/26072512
http://dx.doi.org/10.1093/bioinformatics/btv262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542784/
https://www.ncbi.nlm.nih.gov/pubmed/26072512
http://dx.doi.org/10.1093/bioinformatics/btv262

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