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Misassembly detection using paired-end sequence reads and optical mapping data
Motivation: A crucial problem in genome assembly is the discovery and correction of misassembly errors in draft genomes. We develop a method called misSEQuel that enhances the quality of draft genomes by identifying misassembly errors and their breakpoints using paired-end sequence reads and optical...
Autores principales: | Muggli, Martin D., Puglisi, Simon J., Ronen, Roy, Boucher, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542784/ https://www.ncbi.nlm.nih.gov/pubmed/26072512 http://dx.doi.org/10.1093/bioinformatics/btv262 |
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