Endosialin Expression in Metastatic Melanoma Tumor Microenvironment Vasculature: Potential Therapeutic Implications

Ontuxizumab (MORAb-004) is a humanized recombinant antibody targeting endosialin (TEM-1, CD248). We conducted an analysis of endosialin expression in metastatic melanoma specimens using the anti-endosialin rat anti- MAb 9G5, in order to determine the potential of endosialin as a therapeutic target w...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiyohara, Eiji, Donovan, Nicholas, Takeshima, Ling, Huang, Sharon, Wilmott, James S., Scolyer, Richard A., Jones, Peter, Somers, Elizabeth B., O’Shannessy, Daniel J., Hoon, Dave S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542822/
https://www.ncbi.nlm.nih.gov/pubmed/26085332
http://dx.doi.org/10.1007/s12307-015-0168-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542822/
https://www.ncbi.nlm.nih.gov/pubmed/26085332
http://dx.doi.org/10.1007/s12307-015-0168-8

Ejemplares similares