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Identification of mutations in the HVR1 and PKR-BD regions in HCV-infected patients resistant to PEG-IFNα/RBV therapy

The identification of mutations in the HVR1 region of hepatitis type C virus (HCV) is time-consuming and expensive, and there is a need for a rapid, inexpensive method of screening for these mutations to predict the ineffectiveness of pegylated interferon alpha combined with ribavirin (PEG-IFNα/RBV)...

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Detalles Bibliográficos
Autores principales: Holysz, M., Bialas, K., Migdalski, P., Kmieciak, D., Trzeciak, W. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543409/
https://www.ncbi.nlm.nih.gov/pubmed/25588648
http://dx.doi.org/10.1007/s13353-014-0267-0