GSK‐3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility

Glycogen synthase kinase 3 (GSK‐3) has been linked to regulation of kinesin‐dependent axonal transport in squid and flies, and to indirect regulation of cytoplasmic dynein. We have now found evidence for direct regulation of dynein by mammalian GSK‐3β in both neurons and non‐neuronal cells. GSK‐3β c...

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Detalles Bibliográficos
Autores principales: Gao, Feng J., Hebbar, Sachin, Gao, Xu A., Alexander, Michael, Pandey, Jai P., Walla, Michael D., Cotham, William E., King, Stephen J., Smith, Deanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543430/
https://www.ncbi.nlm.nih.gov/pubmed/26010407
http://dx.doi.org/10.1111/tra.12304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543430/
https://www.ncbi.nlm.nih.gov/pubmed/26010407
http://dx.doi.org/10.1111/tra.12304

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