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GSK‐3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility
Glycogen synthase kinase 3 (GSK‐3) has been linked to regulation of kinesin‐dependent axonal transport in squid and flies, and to indirect regulation of cytoplasmic dynein. We have now found evidence for direct regulation of dynein by mammalian GSK‐3β in both neurons and non‐neuronal cells. GSK‐3β c...
Autores principales: | Gao, Feng J., Hebbar, Sachin, Gao, Xu A., Alexander, Michael, Pandey, Jai P., Walla, Michael D., Cotham, William E., King, Stephen J., Smith, Deanna S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons A/S
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543430/ https://www.ncbi.nlm.nih.gov/pubmed/26010407 http://dx.doi.org/10.1111/tra.12304 |
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