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Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains

Inflammatory responses in the brain, which can be demonstrated by changes in properties of microglia, the brain-resident macrophages, are a common feature of human neurodegenerative diseases. Different monocyte/macrophage phenotypes have been defined by changes in expression of cytokines, receptors...

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Detalles Bibliográficos
Autores principales: Walker, Douglas G., Lue, Lih-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543480/
https://www.ncbi.nlm.nih.gov/pubmed/26286145
http://dx.doi.org/10.1186/s13195-015-0139-9