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Monoacylglycerol Lipase Regulates Fever Response

Cyclooxygenase inhibitors such as ibuprofen have been used for decades to control fever through reducing the levels of the pyrogenic lipid transmitter prostaglandin E2 (PGE(2)). Historically, phospholipases have been considered to be the primary generator of the arachidonic acid (AA) precursor pool...

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Detalles Bibliográficos
Autores principales: Sanchez-Alavez, Manuel, Nguyen, William, Mori, Simone, Moroncini, Gianluca, Viader, Andreu, Nomura, Daniel K., Cravatt, Benjamin F., Conti, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543552/
https://www.ncbi.nlm.nih.gov/pubmed/26287872
http://dx.doi.org/10.1371/journal.pone.0134437