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Monoacylglycerol Lipase Regulates Fever Response
Cyclooxygenase inhibitors such as ibuprofen have been used for decades to control fever through reducing the levels of the pyrogenic lipid transmitter prostaglandin E2 (PGE(2)). Historically, phospholipases have been considered to be the primary generator of the arachidonic acid (AA) precursor pool...
Autores principales: | Sanchez-Alavez, Manuel, Nguyen, William, Mori, Simone, Moroncini, Gianluca, Viader, Andreu, Nomura, Daniel K., Cravatt, Benjamin F., Conti, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543552/ https://www.ncbi.nlm.nih.gov/pubmed/26287872 http://dx.doi.org/10.1371/journal.pone.0134437 |
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