A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated Ca(V)1.2 Calcium Channel Function

L-type voltage-gated Ca(2+) channels (LTCCs) regulate many physiological functions like muscle contraction, hormone secretion, gene expression, and neuronal excitability. Their activity is strictly controlled by various molecular mechanisms. The pore-forming α(1)-subunit comprises four repeated doma...

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Detalles Bibliográficos
Autores principales: Kaur, Gurjot, Pinggera, Alexandra, Ortner, Nadine J., Lieb, Andreas, Sinnegger-Brauns, Martina J., Yarov-Yarovoy, Vladimir, Obermair, Gerald J., Flucher, Bernhard E., Striessnig, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Membrane Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543666/
https://www.ncbi.nlm.nih.gov/pubmed/26100638
http://dx.doi.org/10.1074/jbc.M115.645671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543666/
https://www.ncbi.nlm.nih.gov/pubmed/26100638
http://dx.doi.org/10.1074/jbc.M115.645671

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