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Loss of IRF8 Inhibits the Growth of Diffuse Large B-cell Lymphoma

IRF8 is a transcription factor with a critical role in B lymphocyte development and functions. Its role in human diffuse large B-cell lymphoma (DLBCL), however, remained elusive. In this study, using shRNA-mediated knockdown of IRF8 expression, we found that the loss of IRF8 significantly reduced th...

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Detalles Bibliográficos
Autores principales: Xu, Yulian, Jiang, Lei, Fang, Jianchen, Fang, Rong, Morse, Herbert C., Ouyang, Guifang, Zhou, Jeff X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543755/
https://www.ncbi.nlm.nih.gov/pubmed/26316891
http://dx.doi.org/10.7150/jca.12067