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The Power Decoder Simulator for the Evaluation of Pooled shRNA Screen Performance

RNA interference screening using pooled, short hairpin RNA (shRNA) is a powerful, high-throughput tool for determining the biological relevance of genes for a phenotype. Assessing an shRNA pooled screen’s performance is difficult in practice; one can estimate the performance only by using reproducib...

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Detalles Bibliográficos
Autores principales: Stombaugh, Jesse, Licon, Abel, Strezoska, Žaklina, Stahl, Joshua, Anderson, Sarah Bael, Banos, Michael, van Brabant Smith, Anja, Birmingham, Amanda, Vermeulen, Annaleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543901/
https://www.ncbi.nlm.nih.gov/pubmed/25777298
http://dx.doi.org/10.1177/1087057115576715