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Lamellipodin promotes actin assembly by clustering Ena/VASP proteins and tethering them to actin filaments

Enabled/Vasodilator (Ena/VASP) proteins promote actin filament assembly at multiple locations, including: leading edge membranes, focal adhesions, and the surface of intracellular pathogens. One important Ena/VASP regulator is the mig-10/Lamellipodin/RIAM family of adaptors that promote lamellipod f...

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Detalles Bibliográficos
Autores principales: Hansen, Scott D, Mullins, R Dyche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543927/
https://www.ncbi.nlm.nih.gov/pubmed/26295568
http://dx.doi.org/10.7554/eLife.06585