The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway

Activated Toll-like receptors (TLRs) cluster in lipid rafts and induce pro- and anti-tumor responses. The organization of the assembly is critical to the understanding of how these key receptors control major signaling pathways in the cell. Although several models for individual interactions were pr...

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Detalles Bibliográficos
Autores principales: Guven-Maiorov, Emine, Keskin, Ozlem, Gursoy, Attila, VanWaes, Carter, Chen, Zhong, Tsai, Chung-Jung, Nussinov, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544004/
https://www.ncbi.nlm.nih.gov/pubmed/26293885
http://dx.doi.org/10.1038/srep13128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544004/
https://www.ncbi.nlm.nih.gov/pubmed/26293885
http://dx.doi.org/10.1038/srep13128

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