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The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway
Activated Toll-like receptors (TLRs) cluster in lipid rafts and induce pro- and anti-tumor responses. The organization of the assembly is critical to the understanding of how these key receptors control major signaling pathways in the cell. Although several models for individual interactions were pr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544004/ https://www.ncbi.nlm.nih.gov/pubmed/26293885 http://dx.doi.org/10.1038/srep13128 |