Heterogeneous lineage marker expression in naive embryonic stem cells is mostly due to spontaneous differentiation

Populations of cultured mouse embryonic stem cells (ESCs) exhibit a subfraction of cells expressing uncharacteristically low levels of pluripotency markers such as Nanog. Yet, the extent to which individual Nanog-negative cells are differentiated, both from ESCs and from each other, remains unclear....

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Detalles Bibliográficos
Autores principales: Nair, Gautham, Abranches, Elsa, Guedes, Ana M. V., Henrique, Domingos, Raj, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544010/
https://www.ncbi.nlm.nih.gov/pubmed/26292941
http://dx.doi.org/10.1038/srep13339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544010/
https://www.ncbi.nlm.nih.gov/pubmed/26292941
http://dx.doi.org/10.1038/srep13339

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