Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

Amyotrophic lateral sclerosis is a rapidly progressing neurodegenerative disease associated with protein misfolding and aggregation. Most cases are characterized by TDP-43 positive inclusions, while a minority of familial ALS cases are instead FUS and SOD1 positive respectively. Cells can generate i...

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Detalles Bibliográficos
Autores principales: Farrawell, Natalie E., Lambert-Smith, Isabella A., Warraich, Sadaf T., Blair, Ian P., Saunders, Darren N., Hatters, Danny M., Yerbury, Justin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544019/
https://www.ncbi.nlm.nih.gov/pubmed/26293199
http://dx.doi.org/10.1038/srep13416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544019/
https://www.ncbi.nlm.nih.gov/pubmed/26293199
http://dx.doi.org/10.1038/srep13416

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