Model-Based Once-Daily Darunavir/Ritonavir Dosing Recommendations in Pediatric HIV-1-Infected Patients Aged ≥3 to <12 Years

An existing population pharmacokinetic model of darunavir in adults was updated using pediatric data from two studies evaluating weight-based, once-daily dosing of darunavir/ritonavir (ARIEL, NCT00919854 and DIONE, NCT00915655). The model was then used to provide once-daily dosing recommendations fo...

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Detalles Bibliográficos
Autores principales: Brochot, A, Kakuda, TN, Van De Casteele, T, Opsomer, M, Tomaka, FL, Vermeulen, A, Vis, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544054/
https://www.ncbi.nlm.nih.gov/pubmed/26312164
http://dx.doi.org/10.1002/psp4.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544054/
https://www.ncbi.nlm.nih.gov/pubmed/26312164
http://dx.doi.org/10.1002/psp4.44

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