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The effect of an specific inducible NO synthase inhibitor, S-methylisothiourea hemisulfate on cisplatin-induced nephrotoxicity; gender-related differences

BACKGROUNDS: It has been previously demonstrated that the increase of nitric oxide (NO) level may promote cisplatin (CP)-induced nephrotoxicity. The aim of this study was to investigate the role of inducible NO synthase (iNOS) inhibitor to prevent CP-induced nephrotoxicity. MATERIALS AND METHODS: Fo...

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Detalles Bibliográficos
Autores principales: Ghayyoomi, Mansooreh, Soltani, Nepton, Nematbakhsh, Mehdi, Moslemi, Fatemeh, Talebi, Ardeshir, Shirdavani, Soheila, Razmjoo, Farzaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544122/
https://www.ncbi.nlm.nih.gov/pubmed/26322278
http://dx.doi.org/10.4103/2277-9175.161223