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Development of telmisartan in the therapy of spinal cord injury: pre-clinical study in rats

BACKGROUND: Decrease of peroxisome proliferator-activated receptors-δ (PPARδ) expression has been observed after spinal cord injury (SCI). Increase of PPARδ may improve the damage in SCI. Telmisartan, the antihypertensive agent, has been mentioned to increase the expression of PPARδ. Thus, we are go...

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Detalles Bibliográficos
Autores principales: Lin, Chien-Min, Tsai, Jo-Ting, Chang, Chen Kuei, Cheng, Juei-Tang, Lin, Jia-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544623/
https://www.ncbi.nlm.nih.gov/pubmed/26316709
http://dx.doi.org/10.2147/DDDT.S86616