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Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

Mucosal damage to the gastrointestinal (GI) tract with resulting microbial translocation is hypothesized to significantly contribute to the heightened and persistent chronic inflammation and immune activation characteristic to HIV infection. Here we employ a non-human primate model of chemically ind...

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Detalles Bibliográficos
Autores principales: Hao, Xing Pei, Lucero, Carissa M., Turkbey, Baris, Bernardo, Marcelino L., Morcock, David R., Deleage, Claire, Trubey, Charles M., Smedley, Jeremy, Klatt, Nichole R., Giavedoni, Luis D., Kristoff, Jan, Xu, Amy, Del Prete, Gregory Q., Keele, Brandon F., Rao, Srinivas S., Alvord, W. Gregory, Choyke, Peter L., Lifson, Jeffrey D., Brenchley, Jason M., Apetrei, Cristian, Pandrea, Ivona, Estes, Jacob D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544774/
https://www.ncbi.nlm.nih.gov/pubmed/26282376
http://dx.doi.org/10.1038/ncomms9020