Na,K-ATPase β(1)-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity

BACKGROUND: The Sonic hedgehog (Shh) signaling pathway plays an important role in cerebellar development, and mutations leading to hyperactive Shh signaling have been associated with certain forms of medulloblastoma, a common form of pediatric brain cancer. While the fundamentals of this pathway are...

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Detalles Bibliográficos
Autores principales: Lee, Seung Joon, Litan, Alisa, Li, Zhiqin, Graves, Bruce, Lindsey, Stephan, Barwe, Sonali P., Langhans, Sigrid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544806/
https://www.ncbi.nlm.nih.gov/pubmed/26286140
http://dx.doi.org/10.1186/s12943-015-0430-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544806/
https://www.ncbi.nlm.nih.gov/pubmed/26286140
http://dx.doi.org/10.1186/s12943-015-0430-1

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