Cargando…
Na,K-ATPase β(1)-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity
BACKGROUND: The Sonic hedgehog (Shh) signaling pathway plays an important role in cerebellar development, and mutations leading to hyperactive Shh signaling have been associated with certain forms of medulloblastoma, a common form of pediatric brain cancer. While the fundamentals of this pathway are...
Autores principales: | Lee, Seung Joon, Litan, Alisa, Li, Zhiqin, Graves, Bruce, Lindsey, Stephan, Barwe, Sonali P., Langhans, Sigrid A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544806/ https://www.ncbi.nlm.nih.gov/pubmed/26286140 http://dx.doi.org/10.1186/s12943-015-0430-1 |
Ejemplares similares
-
Inhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma
por: Wolle, Daniel, et al.
Publicado: (2014) -
Sonic Hedgehog-Induced Histone Deacetylase Activation Is Required for Cerebellar Granule Precursor Hyperplasia in Medulloblastoma
por: Lee, Seung Joon, et al.
Publicado: (2013) -
Transcriptional regulators of Na,K-ATPase subunits
por: Li, Zhiqin, et al.
Publicado: (2015) -
EGF-induced sodium influx regulates EGFR trafficking through HDAC6 and tubulin acetylation
por: Lee, Seung Joon, et al.
Publicado: (2015) -
Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma
por: Jenkins, Noah C, et al.
Publicado: (2014)