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Crude triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non-alcoholic fatty liver disease model

BACKGROUND: Ilex latifolia Thunb. (Da Ye Dong Qing) is used for weight loss and for its antidiabetic effects. This study aims to investigate the beneficial effects and potential mechanisms of action of crude triterpenoid saponins (CTS) from I. latifolia in a mouse model of high-fat diet (HFD)-induce...

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Detalles Bibliográficos
Autores principales: Feng, Rui-Bing, Fan, Chun-Lin, Liu, Qing, Liu, Zhong, Zhang, Wei, Li, Yao-Lan, Tang, Wei, Wang, Ying, Li, Man-Mei, Ye, Wen-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544818/
https://www.ncbi.nlm.nih.gov/pubmed/26300958
http://dx.doi.org/10.1186/s13020-015-0054-9