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Generation of Naïve Bovine Induced Pluripotent Stem Cells Using PiggyBac Transposition of Doxycycline-Inducible Transcription Factors

Generation of pluripotent stem cells (PSCs) in large domestic animals has achieved only limited success; most of the PSCs obtained to date have been classified as primed PSCs, which possess very little capacity to produce chimeric offspring. By contrast, mouse PSCs have been classified as naïve PSCs...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Takamasa, Tsukiyama, Tomoyuki, Kimura, Koji, Matsuyama, Shuichi, Minami, Naojiro, Yamada, Masayasu, Imai, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544884/
https://www.ncbi.nlm.nih.gov/pubmed/26287611
http://dx.doi.org/10.1371/journal.pone.0135403