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Differential Telomere Shortening in Blood versus Arteries in an Animal Model of Type 2 Diabetes

Vascular dysfunction is an early feature of diabetic vascular disease, due to increased oxidative stress and reduced nitric oxide (NO) bioavailability. This can lead to endothelial cell senescence and clinical complications such as stroke. Cells can become senescent by shortened telomeres and oxidat...

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Detalles Bibliográficos
Autores principales: Tajbakhsh, Samira, Aliakbari, Kamelya, Hussey, Damian J., Lower, Karen M., Donato, Anthony J., Sokoya, Elke M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545169/
https://www.ncbi.nlm.nih.gov/pubmed/26346823
http://dx.doi.org/10.1155/2015/153829