Folate-dependent hydrolysis of acetyl-coenzyme A by recombinant human and rodent arylamine N-acetyltransferases

Arylamine N-acetyltransferases (NATs) are drug and xenobiotic metabolizing enzymes that catalyze the N-acetylation of arylamines and hydrazines and the O-acetylation of N-hydroxy-arylamines. Recently, studies report that human NAT1 and mouse Nat2 hydrolyze acetyl-coenzyme A (AcCoA) into acetate and...

Descripción completa

Detalles Bibliográficos
Autores principales: Stepp, Marcus W., Mamaliga, Galina, Doll, Mark A., States, J. Christopher, Hein, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545580/
https://www.ncbi.nlm.nih.gov/pubmed/26309907
http://dx.doi.org/10.1016/j.bbrep.2015.07.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545580/
https://www.ncbi.nlm.nih.gov/pubmed/26309907
http://dx.doi.org/10.1016/j.bbrep.2015.07.011

Ejemplares similares