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Tumor and red bone marrow dosimetry: comparison of methods for prospective treatment planning in pretargeted radioimmunotherapy

BACKGROUND: Red bone marrow (RBM) toxicity is dose-limiting in (pretargeted) radioimmunotherapy (RIT). Previous blood-based and two-dimensional (2D) image-based methods have failed to show a clear dose-response relationship. We developed a three-dimensional (3D) image-based RBM dosimetry approach us...

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Detalles Bibliográficos
Autores principales: Woliner-van der Weg, Wietske, Schoffelen, Rafke, Hobbs, Robert F, Gotthardt, Martin, Goldenberg, David M, Sharkey, Robert M, Slump, Cornelis H, van der Graaf, Winette TA, Oyen, Wim JG, Boerman, Otto C, Sgouros, George, Visser, Eric P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545615/
https://www.ncbi.nlm.nih.gov/pubmed/26501807
http://dx.doi.org/10.1186/s40658-014-0104-x