Double inv(3)(q21q26.2) in acute myeloid leukemia is resulted from an acquired copy neutral loss of heterozygosity of chromosome 3q and associated with disease progression

BACKGROUND: Acute myeloid leukemia (AML) with inv(3)(q21q26.2)/t(3;3)(q21;q26.2) is a distinct clinicopathologic entity with a poor prognosis. However, double inv(3)(q21q26.2) is extremely rare in AML. We report here 3 cases analyzed by oligonucleotide microarray comparative genomic hybridization (a...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Jun, Patel, Keyur P., Bai, Bing, Liu, Ching-Hua, Tang, Guilin, Kantarjian, Hagop M., Tang, Zhenya, Abraham, Ronald, Luthra, Rajyalakshmi, Medeiros, L. Jeffrey, Lin, Pei, Lu, Xinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545786/
https://www.ncbi.nlm.nih.gov/pubmed/26300976
http://dx.doi.org/10.1186/s13039-015-0171-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545786/
https://www.ncbi.nlm.nih.gov/pubmed/26300976
http://dx.doi.org/10.1186/s13039-015-0171-2

Ejemplares similares