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P-Glycoprotein Induction Ameliorates Colistin Induced Nephrotoxicity in Cultured Human Proximal Tubular Cells

The pathogenesis of colistin induced nephrotoxicity is poorly understood. Currently there are no effective therapeutic or prophylactic agents available. This study was aimed to determine the mechanism of colistin induced nephrotoxicity and to determine whether P-glycoprotein (P-gp) induction could p...

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Detalles Bibliográficos
Autores principales: Lee, Sun-hyo, Kim, Jin-sun, Ravichandran, Kameswaran, Gil, Hyo-Wook, Song, Ho-yeon, Hong, Sae-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545883/
https://www.ncbi.nlm.nih.gov/pubmed/26287374
http://dx.doi.org/10.1371/journal.pone.0136075