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Assessing breast cancer cell lines as tumour models by comparison of mRNA expression profiles

INTRODUCTION: Breast cancer researchers use cell lines to model myriad phenomena ranging from DNA repair to cancer stem cell phenotypes. Though appropriate, and even requisite, for many studies, the suitability of cell lines as tumour models has come into question owing to possibilities of tissue cu...

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Detalles Bibliográficos
Autores principales: Vincent, Krista Marie, Findlay, Scott D., Postovit, Lynne Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545915/
https://www.ncbi.nlm.nih.gov/pubmed/26289960
http://dx.doi.org/10.1186/s13058-015-0613-0