Foxp3-modified bone marrow mesenchymal stem cells promotes liver allograft tolerance through the generation of regulatory T cells in rats

BACKGROUND: The transcription factor forkhead box P3 (Foxp3) is a master regulatory gene necessary for the development and function of CD4(+)CD25(+) regulatory T cells (Tregs). Mesenchymal stem cells (MSC) have recently emerged as promising candidates for cell-based immunosuppression/tolerance induc...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Haizhi, Chen, Guangshun, Huang, Yaxun, Si, Zhongzhou, Li, Jiequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545923/
https://www.ncbi.nlm.nih.gov/pubmed/26293578
http://dx.doi.org/10.1186/s12967-015-0638-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545923/
https://www.ncbi.nlm.nih.gov/pubmed/26293578
http://dx.doi.org/10.1186/s12967-015-0638-2

Ejemplares similares