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LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2

High cholesterol and diabetes are major risk factors for atherosclerosis. Regression of atherosclerosis is mediated in part by the Liver X Receptor (LXR) through the induction of genes involved in cholesterol transport and efflux. In the context of diabetes, regression of atherosclerosis is impaired...

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Detalles Bibliográficos
Autores principales: Hussein, Maryem A., Shrestha, Elina, Ouimet, Mireille, Barrett, Tessa J., Leone, Sarah, Moore, Kathryn J., Hérault, Yann, Fisher, Edward A., Garabedian, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545936/
https://www.ncbi.nlm.nih.gov/pubmed/26288135
http://dx.doi.org/10.1371/journal.pone.0135218